The AZI2 Antibody from MyBioSource.com is a Rabbit Polyclonal antibody to AZI2, and Miscellaneous. This antibody recognizes Human, Mouse, and Rat antigen. The AZI2 Antibody has been validated for the following applications: Western Blot.
Description
Adapter protein which binds TBK1 and IKBKE playing a role in antiviral innate immunity. Activates serine/threonine-protein kinase TBK1 and facilitates its oligomerization. Enhances the phosphorylation of NF-kappa-B p65 subunit RELA by TBK1. Promotes TBK1-induced as well as TNF-alpha or PMA-induced activation of NF-kappa-B. Participates in IFNB promoter activation via TICAM1.Fujita F., Mol. Cell. Biol. 23:7780-7793(2003).Ota T., Nat. Genet. 36:40-45(2004).Sasai M., J. Immunol. 174:27-30(2005)